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A novel role of IL-17–producing lymphocytes in mediating lytic bone disease in multiple myeloma
Osteoclast (OC)–mediated lytic bone disease remains a cause of major morbidity in multiple myeloma. Here we demonstrate the critical role of interleukin-17–producing marrow infiltrating lymphocytes (MILs) in OC activation and development of bone lesions in myeloma patients. Unlike MILs from normal b...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4017298/ https://ncbi.nlm.nih.gov/pubmed/20664052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-283895 |
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