Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells

Angiogenesis is a key pathological feature of experimental and human steatohepatitis, a common chronic liver disease that is associated with obesity. We demonstrated that hepatocytes generated a type of membrane-bound vesicle, microparticles, in response to conditions that mimicked the lipid accumul...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Povero, Davide, Eguchi, Akiko, Niesman, Ingrid R., Andronikou, Nektaria, de Mollerat du Jeu, Xavier, Mulya, Anny, Berk, Michael, Lazic, Milos, Thapaliya, Samjana, Parola, Maurizio, Patel, Hemal H., Feldstein, Ariel E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016801/
https://ncbi.nlm.nih.gov/pubmed/24106341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004512
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