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Effect of genetic deletion and pharmacological antagonism of P2X7 receptors in a mouse animal model of migraine

BACKGROUND: Purine receptors participate in peripheral and central sensitization and are associated with migraine headache. We investigated the role of P2X7 receptor (P2X7) in a nitroglycerin (NTG)-induced mouse model of migraine. METHODS: Intraperitoneal NTG injection (15 mg/kg) triggered thermal h...

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Detalhes bibliográficos
Main Authors: Gölöncsér, Flóra, Sperlágh, Beáta
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016653/
https://ncbi.nlm.nih.gov/pubmed/24885962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1129-2377-15-24
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