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Effect of genetic deletion and pharmacological antagonism of P2X7 receptors in a mouse animal model of migraine
BACKGROUND: Purine receptors participate in peripheral and central sensitization and are associated with migraine headache. We investigated the role of P2X7 receptor (P2X7) in a nitroglycerin (NTG)-induced mouse model of migraine. METHODS: Intraperitoneal NTG injection (15 mg/kg) triggered thermal h...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4016653/ https://ncbi.nlm.nih.gov/pubmed/24885962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1129-2377-15-24 |
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