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Genetically engineered endostatin-lidamycin fusion proteins effectively inhibit tumor growth and metastasis
BACKGROUND: Endostatin (ES) inhibits endothelial cell proliferation, migration, invasion, and tube formation. It also shows antiangiogenesis and antitumor activities in several animal models. Endostatin specifically targets tumor vasculature to block tumor growth. Lidamycin (LDM), which consists of...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4016579/ https://ncbi.nlm.nih.gov/pubmed/24128285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-479 |
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