Eribulin mesylate exerts specific gene expression changes in pericytes and shortens pericyte-driven capillary network in vitro

BACKGROUND: Eribulin mesylate is a synthetic macrocyclic ketone analog of the marine sponge natural product halichondrin B. Eribulin is a tubulin-binding drug and approved in many countries worldwide for treatment of certain patients with advanced breast cancer. Here we investigated antiproliferativ...

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Bibliographische Detailangaben
Hauptverfasser: Agoulnik, Sergei I, Kawano, Satoshi, Taylor, Noel, Oestreicher, Judith, Matsui, Junji, Chow, Jesse, Oda, Yoshiya, Funahashi, Yasuhiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016419/
https://ncbi.nlm.nih.gov/pubmed/24581301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-824X-6-3
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