Gene Expression Profiling Reveals Epithelial Mesenchymal Transition (EMT) Genes Can Selectively Differentiate Eribulin Sensitive Breast Cancer Cells

OBJECTIVES: Eribulin mesylate is a synthetic macrocyclic ketone analog of the marine sponge natural product halichondrin B. Eribulin is a mechanistically unique inhibitor of microtubule dynamics. In this study, we investigated whether selective signal pathways were associated with eribulin activity...

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Detalhes bibliográficos
Main Authors: Dezső, Zoltán, Oestreicher, Judith, Weaver, Amy, Santiago, Stephanie, Agoulnik, Sergei, Chow, Jesse, Oda, Yoshiya, Funahashi, Yasuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149521/
https://ncbi.nlm.nih.gov/pubmed/25171249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106131
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