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Association of candidate single nucleotide polymorphisms with somatic mutation of the epidermal growth factor receptor pathway

BACKGROUND: Tumour growth in colorectal cancer and other solid cancers is frequently supported by activating mutations in the epidermal growth factor receptor (EGFR) signaling pathway (Patholog Res Int 2011:932932, 2011). Treatment of metastatic colorectal cancer with targeted anti-EGFR therapeutics...

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Bibliografiske detaljer
Main Authors: Wormald, Samuel, Milla, Liz, O’Connor, Liam
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016273/
https://ncbi.nlm.nih.gov/pubmed/24152305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-6-43
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