Expression level of hTERT is regulated by somatic mutation and common single nucleotide polymorphism at promoter region in glioblastoma

We investigated the role of somatic mutations and a common single nucleotide polymorphism (SNP) in the hTERT promoter region on hTERT expression and clinical outcomes. The hTERT promoter region was sequenced from 48 glioblastomas. hTERT expression was analyzed by quantitative real time-PCR. The asso...

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Bibliografski detalji
Glavni autori: Park, Chul-Kee, Lee, Se-Hoon, Kim, Ji Young, Kim, Ja Eun, Kim, Tae Min, Lee, Soon-Tae, Choi, Seung Hong, Park, Sung-Hye, Kim, Il Han
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2014
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102818/
https://ncbi.nlm.nih.gov/pubmed/24930669
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