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Gastrointestinal stromal tumors: a case-only analysis of single nucleotide polymorphisms and somatic mutations
BACKGROUND: Gastrointestinal stromal tumors are rare soft tissue sarcomas that typically develop from mesenchymal cells with acquired gain-in-function mutations in KIT or PDGFRA oncogenes. These somatic mutations have been well-characterized, but little is known about inherited genetic risk factors....
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3827940/ https://ncbi.nlm.nih.gov/pubmed/24159917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3329-3-12 |
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