Aurora-A Mitotic Kinase Induces Endocrine Resistance through Down-Regulation of ERα Expression in Initially ERα+ Breast Cancer Cells

Development of endocrine resistance during tumor progression represents a major challenge in the management of estrogen receptor alpha (ERα) positive breast tumors and is an area under intense investigation. Although the underlying mechanisms are still poorly understood, many studies point towards t...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Opyrchal, Mateusz, Salisbury, Jeffrey L., Zhang, Shuya, McCubrey, James, Hawse, John, Goetz, Mattew P., Lomberk, Gwen A., Haddad, Tufia, Degnim, Amy, Lange, Carol, Ingle, James N., Galanis, Evanthia, D'Assoro, Antonino B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016211/
https://ncbi.nlm.nih.gov/pubmed/24816249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096995
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk