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Synapse elimination and learning rules coregulated by MHC Class I H2-Db
The formation of precise connections between retina and LGN involves the activity-dependent elimination of some synapses, with strengthening and retention of others. Here we show that the MHC Class I (MHCI) molecule H2-Db is necessary and sufficient for synapse elimination in the retinogeniculate sy...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4016165/ https://ncbi.nlm.nih.gov/pubmed/24695230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13154 |
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