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Regulation of CNS synapses by neuronal MHC class I

Until recently, neurons in the healthy brain were considered immune-privileged because they did not appear to express MHC class I (MHCI). However, MHCI mRNA was found to be regulated by neural activity in the developing visual system and has been detected in other regions of the uninjured brain. Her...

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Detalhes bibliográficos
Main Authors: Goddard, C. Alex, Butts, Daniel A., Shatz, Carla J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871870/
https://ncbi.nlm.nih.gov/pubmed/17420446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702023104
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