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In Multiple Myeloma, 14q32 Translocations Are Non-Random Chromosomal Fusions Driving High Expression Levels of the Respective Partner Genes
In studies of patients with multiple myeloma (MM), gene expression profiling (GEP) of myeloma cells demonstrates substantially higher expression of MMSET, FGFR3, CCND3, CCND1, MAF, and MAFB—the partner genes of 14q32 translocations—than GEP of plasma cells from healthy individuals. Interphase fluore...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4016160/ https://ncbi.nlm.nih.gov/pubmed/24638926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22165 |
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