IL-13 signaling via IL-13Rα(2) triggers TGF-β(1)-dependent allograft fibrosis

BACKGROUND: Allograft fibrosis still remains a critical problem in transplantation, including heart transplantation. The IL-13/TGF-β(1) interaction has previously been identified as a key pathway orchestrating fibrosis in different inflammatory immune disorders. Here we investigate if this pathway i...

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Detalhes bibliográficos
Main Authors: Brunner, Stefan M, Schiechl, Gabriela, Kesselring, Rebecca, Martin, Maria, Balam, Saidou, Schlitt, Hans J, Geissler, Edward K, Fichtner-Feigl, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016099/
https://ncbi.nlm.nih.gov/pubmed/24143891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-1440-2-16
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