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Restoration of Tumor Immune Surveillance via Targeting of IL-13Receptor-α(2)
In previous studies we described a “counter-immunosurveillance” mechanism initiated by tumor-activated, IL-13-producing NKT cells that signal Gr-1(+) cells to produce TGF-β(1), a cytokine that suppresses the activity of tumor-inhibiting cytolytic CD8(+) T cells. Here we show that in two tumor models...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746996/ https://ncbi.nlm.nih.gov/pubmed/18451175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5301 |
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