Restoration of Tumor Immune Surveillance via Targeting of IL-13Receptor-α(2)

In previous studies we described a “counter-immunosurveillance” mechanism initiated by tumor-activated, IL-13-producing NKT cells that signal Gr-1(+) cells to produce TGF-β(1), a cytokine that suppresses the activity of tumor-inhibiting cytolytic CD8(+) T cells. Here we show that in two tumor models...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fichtner-Feigl, Stefan, Terabe, Masaki, Kitani, Atsushi, Young, Cheryl A., Fuss, Ivan, Geissler, Edward K., Schlitt, Hans-Jürgen, Berzofsky, Jay A., Strober, Warren
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746996/
https://ncbi.nlm.nih.gov/pubmed/18451175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5301
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