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Deletion of Foxp3(+) regulatory T cells in genetically targeted mice supports development of intestinal inflammation
BACKGROUND: Mice lacking Foxp3(+) regulatory T (Treg) cells develop severe tissue inflammation in lung, skin, and liver with premature death, whereas the intestine remains uninflamed. This study aims to demonstrate the importance of Foxp3(+) Treg for the activation of T cells and the development of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449180/ https://ncbi.nlm.nih.gov/pubmed/22849659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-12-97 |
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