Epidermal growth factor binding induces a conformational change in the external domain of its receptor.

To study the properties of the extracellular epidermal growth factor (EGF) binding domain of the human EGF receptor, we have infected insect cells with a suitably engineered baculovirus vector containing the cDNA encoding the entire ectodomain of the parent molecule. This resulted in a correctly fol...

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Detalhes bibliográficos
Main Authors: Greenfield, C, Hiles, I, Waterfield, M D, Federwisch, M, Wollmer, A, Blundell, T L, McDonald, N
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC401594/
https://ncbi.nlm.nih.gov/pubmed/2591370
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