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Conformational changes accompany phosphorylation of the epidermal growth factor receptor C-terminal domain

The precise regulation of epidermal growth factor receptor (EGFR) signaling is crucial to its function in cellular growth control. Various studies have suggested that the C-terminal phosphorylation domain, itself a substrate for the EGFR kinase activity, exerts a regulatory influence upon it, althou...

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Autori principali: Lee, Nam Y., Koland, John G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253217/
https://ncbi.nlm.nih.gov/pubmed/16199664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051630305
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