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Clinical and functional characterization of the Pro1198Leu ABCC8 gene mutation associated with permanent neonatal diabetes mellitus
AIMS/INTRODUCTION: The adenosine triphosphate (ATP)‐sensitive potassium (K(ATP)) channel is a key component of insulin secretion in pancreatic β‐cells. Activating mutations in ABCC8 encoding for the sulfonylurea receptor subunit of the K(ATP) channel have been associated with the development of neon...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Wiley-Blackwell
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4015663/ https://ncbi.nlm.nih.gov/pubmed/24843665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12049 |
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