Pro198Leu missense polymorphism of the glutathione peroxidase 1 gene might be a common genetic predisposition of distal symmetric polyneuropathy and macrovascular disease in Japanese type 2 diabetic patients

Aims/Introduction:  We have previously reported that the Pro198Leu missense polymorphism in the glutathione peroxidase 1 (GPx‐1) gene was associated with frequent macrovascular disease (MVD). Our goal was to examine whether the GPx‐1 genotype is associated with diabetic neuropathy. Materials and Met...

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Hauptverfasser: Matsuno, Shohei, Sasaki, Hideyuki, Yamasaki, Hiroshi, Yamaoka, Hiroyuki, Ogawa, Kenichi, Nakatani, Muneki, Hamanishi, Tohru, Doi, Asako, Nakano, Yoshio, Wakasaki, Hisao, Furuta, Hiroto, Nishi, Masahiro, Akamizu, Takashi, Nanjo, Kishio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014907/
https://ncbi.nlm.nih.gov/pubmed/24843532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.2040-1124.2011.00127.x
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