The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland

The mammary gland is a very dynamic organ that undergoes continuous remodeling. The critical regulators of this process are not fully understood. Here we identify the microRNA cluster miR-424(322)/503 as an important regulator of epithelial involution after pregnancy. Through the generation of a kno...

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Autors principals: Llobet-Navas, David, Rodríguez-Barrueco, Ruth, Castro, Verónica, Ugalde, Alejandro P., Sumazin, Pavel, Jacob-Sendler, Damian, Demircan, Berna, Castillo-Martín, Mireia, Putcha, Preeti, Marshall, Netonia, Villagrasa, Patricia, Chan, Joseph, Sanchez-Garcia, Félix, Pe’er, Dana, Rabadán, Raul, Iavarone, Antonio, Cordón-Cardó, Carlos, Califano, Andrea, López-Otín, Carlos, Ezhkova, Elena, Silva, Jose M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015488/
https://ncbi.nlm.nih.gov/pubmed/24636986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.237404.114
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