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MiR-322/424 and -503 Are Induced during Muscle Differentiation and Promote Cell Cycle Quiescence and Differentiation by Down-Regulation of Cdc25A

Induction of a G1 phase cell cycle arrest, caused primarily by the inhibition of cyclin-dependent-kinase 2 (cdk2), is a critical step in the differentiation of myoblasts into myotubes. Here, we report that two microRNAs, miR-322/424 and miR-503, are induced and promote cdk2 inhibition during myogene...

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Bibliografiske detaljer
Main Authors: Sarkar, Sukumar, Dey, Bijan K., Dutta, Anindya
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893979/
https://ncbi.nlm.nih.gov/pubmed/20462953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-01-0062
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