Runx1 and Cbfβ regulate the development of Flt3(+) dendritic cell progenitors and restrict myeloproliferative disorder

Runx1 and Cbfβ are critical for the establishment of definitive hematopoiesis and are implicated in leukemic transformation. Despite the absolute requirements for these factors in the development of hematopoietic stem cells and lymphocytes, their roles in the development of bone marrow progenitor su...

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Main Authors: Satpathy, Ansuman T., Briseño, Carlos G., Cai, Xiongwei, Michael, Drew G., Chou, Chun, Hsiung, Sunnie, Bhattacharya, Deepta, Speck, Nancy A., Egawa, Takeshi
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2014
Teme:
Hematopoiesis and Stem Cells
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014839/
https://ncbi.nlm.nih.gov/pubmed/24677539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-539643
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