Standardizing Benchmark Dose Calculations to Improve Science-Based Decisions in Human Health Assessments

Background: Benchmark dose (BMD) modeling computes the dose associated with a prespecified response level. While offering advantages over traditional points of departure (PODs), such as no-observed-adverse-effect-levels (NOAELs), BMD methods have lacked consistency and transparency in application, i...

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Autori principali: Wignall, Jessica A., Shapiro, Andrew J., Wright, Fred A., Woodruff, Tracey J., Chiu, Weihsueh A., Guyton, Kathryn Z., Rusyn, Ivan
Natura: Artigo
Lingua:Inglês
Pubblicazione: NLM-Export 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014768/
https://ncbi.nlm.nih.gov/pubmed/24569956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1307539
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