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Common Drugs Inhibit Human Organic Cation Transporter 1 (OCT1)-Mediated Neurotransmitter Uptake

The human organic cation transporter 1 (OCT1) is a polyspecific transporter involved in the uptake of positively charged and neutral small molecules in the liver. To date, few endogenous compounds have been identified as OCT1 substrates; more importantly, the effect of drugs on endogenous substrate...

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Detalhes bibliográficos
Main Authors: Boxberger, Kelli H., Hagenbuch, Bruno, Lampe, Jed N.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014663/
https://ncbi.nlm.nih.gov/pubmed/24688079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.113.055095
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