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Regulation of GluA1 α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptor Function by Protein Kinase C at Serine-818 and Threonine-840

Three residues within the AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor subunit GluA1 C terminus (Ser818, Ser831, Thr840) can be phosphorylated by Ca(2+)/phospholipid-dependent protein kinase (PKC). Here, we show that PKC phosphorylation of GluA1 Ser818 or Thr840 enhances the...

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Autori principali: Jenkins, Meagan A., Wells, Gordon, Bachman, Julia, Snyder, James P., Jenkins, Andrew, Huganir, Richard L., Oswald, Robert E., Traynelis, Stephen F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014661/
https://ncbi.nlm.nih.gov/pubmed/24452473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.091488
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