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PKC phosphorylates GluA1-Ser831 to enhance AMPA receptor conductance

AMPA receptors mediate fast excitatory synaptic transmission in the brain, and are dynamically regulated by phosphorylation of multiple residues within the C-terminal domain. CaMKII phosphorylates Ser831 within the AMPA receptor GluA1 subunit to increase single channel conductance, and biochemical s...

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Detalhes bibliográficos
Main Authors: Jenkins, Meagan A., Traynelis, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367675/
https://ncbi.nlm.nih.gov/pubmed/22373567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.18648
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