S-nitrosylation of AMPA receptor GluA1 regulates phosphorylation, single-channel conductance, and endocytosis

NMDA receptor activation can elicit synaptic plasticity by augmenting conductance of the AMPA receptor GluA1 subsequent to phosphorylation at S831 by Ca(2+)-dependent kinases. NMDA receptor activation also regulates synaptic plasticity by causing endocytosis of AMPA receptor GluA1. We demonstrate a...

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Autors principals: Selvakumar, Balakrishnan, Jenkins, Meagan A., Hussain, Natasha K., Huganir, Richard L., Traynelis, Stephen F., Snyder, Solomon H.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549090/
https://ncbi.nlm.nih.gov/pubmed/23277581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221295110
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