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Directed Evolution of Improved Zinc Finger Methyltransferases

The ability to target DNA methylation toward a single, user-designated CpG site in vivo may have wide applicability for basic biological and biomedical research. A tool for targeting methylation toward single sites could be used to study the effects of individual methylation events on transcription,...

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Détails bibliographiques
Auteurs principaux: Chaikind, Brian, Ostermeier, Marc
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014571/
https://ncbi.nlm.nih.gov/pubmed/24810747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096931
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