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Targeted DNA Methylation Using an Artificially Bisected M.HhaI Fused to Zinc Fingers

Little is known about the effects of single DNA methylation events on gene transcription. The ability to direct the methylation toward a single unique site within a genome would have broad use as a tool to study the effects of specific epigenetic changes on transcription. A targeted enzyme might als...

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Bibliografski detalji
Glavni autori: Chaikind, Brian, Kilambi, Krishna Praneeth, Gray, Jeffrey J., Ostermeier, Marc
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439449/
https://ncbi.nlm.nih.gov/pubmed/22984575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044852
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