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Targeted DNA Methylation Using an Artificially Bisected M.HhaI Fused to Zinc Fingers

Little is known about the effects of single DNA methylation events on gene transcription. The ability to direct the methylation toward a single unique site within a genome would have broad use as a tool to study the effects of specific epigenetic changes on transcription. A targeted enzyme might als...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Chaikind, Brian, Kilambi, Krishna Praneeth, Gray, Jeffrey J., Ostermeier, Marc
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439449/
https://ncbi.nlm.nih.gov/pubmed/22984575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044852
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