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An engineered split M.HhaI-zinc finger fusion lacks the intended methyltransferase specificity
The ability to site-specifically methylate DNA in vivo would have wide applicability to the study of basic biomedical problems as well as enable studies on the potential of site-specific DNA methylation as a therapeutic strategy for the treatment of diseases. Natural DNA methyltransferases lack the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586766/ https://ncbi.nlm.nih.gov/pubmed/18835252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.09.099 |
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