Anomeric DNA quadruplexes: Modified thrombin aptamers

Thrombin-binding aptamer (TBA) is a 15-nt DNA oligomer that efficiently inhibits thrombin. It has been shown that TBA folds into an anti-parallel unimolecular G-quadruplex. Its three-dimensional chair-like structure consists of two G-tetrads connected by TT and TGT loops. TBA undergoes fast degradat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kolganova, Natalia A, Varizhuk, Anna M, Novikov, Roman A, Florentiev, Vladimir L, Pozmogova, Galina E, Borisova, Olga F, Shchyolkina, Anna K, Smirnov, Igor P, Kaluzhny, Dmitry N, Timofeev, Edward N
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2014
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014524/
https://ncbi.nlm.nih.gov/pubmed/25483931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adna.28422
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