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Genetic Interactions with Sex Make a Relatively Small Contribution to the Heritability of Complex Traits in Mice
The extent to which sex-specific genetic effects contribute to phenotypic variation is largely unknown. We applied a novel Bayesian method, sparse partitioning, to detect gene by sex (GxS) and gene by gene (GxG) quantitative loci (QTLs) in 1,900 outbred heterogeneous stock mice. In an analysis of 55...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4014490/ https://ncbi.nlm.nih.gov/pubmed/24811081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096450 |
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