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Epigenetic Changes Modulate Schistosome Egg Formation and Are a Novel Target for Reducing Transmission of Schistosomiasis

Treatment and control of schistosomiasis relies on the only available drug, praziquantel, and the search for alternative chemotherapeutic agents is therefore urgent. Egg production is required for the transmission and immunopathology of schistosomiasis and females of S. mansoni lay 300 eggs daily. A...

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Main Authors: Carneiro, Vitor Coutinho, de Abreu da Silva, Isabel Caetano, Torres, Eduardo José Lopes, Caby, Stephany, Lancelot, Julien, Vanderstraete, Mathieu, Furdas, Silviya D., Jung, Manfred, Pierce, Raymond J., Fantappié, Marcelo Rosado
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014452/
https://ncbi.nlm.nih.gov/pubmed/24809504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004116
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