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Epigenetic Changes Modulate Schistosome Egg Formation and Are a Novel Target for Reducing Transmission of Schistosomiasis

Treatment and control of schistosomiasis relies on the only available drug, praziquantel, and the search for alternative chemotherapeutic agents is therefore urgent. Egg production is required for the transmission and immunopathology of schistosomiasis and females of S. mansoni lay 300 eggs daily. A...

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Detalhes bibliográficos
Main Authors: Carneiro, Vitor Coutinho, de Abreu da Silva, Isabel Caetano, Torres, Eduardo José Lopes, Caby, Stephany, Lancelot, Julien, Vanderstraete, Mathieu, Furdas, Silviya D., Jung, Manfred, Pierce, Raymond J., Fantappié, Marcelo Rosado
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014452/
https://ncbi.nlm.nih.gov/pubmed/24809504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004116
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