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Compound library screening identified Akt/PKB kinase pathway inhibitors as potential key molecules for the development of new chemotherapeutics against schistosomiasis

Protein kinases (PKs) are one of the largest protein families in most eukaryotic organisms. These enzymes are involved in the control of cell proliferation, differentiation and metabolism and a large number of the anticancer drugs currently used are directed against PKs. The structure and function o...

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Detalhes bibliográficos
Publicado no:Int J Parasitol Drugs Drug Resist
Main Authors: Morel, Marion, Vanderstraete, Mathieu, Cailliau, Katia, Lescuyer, Arlette, Lancelot, Julien, Dissous, Colette
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266776/
https://ncbi.nlm.nih.gov/pubmed/25516836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2014.09.004
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