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Phosphorylation of ARPP19 by protein kinase A prevents meiosis resumption in Xenopus oocytes
During oogenesis, oocytes are arrested in prophase and resume meiosis by activating the kinase Cdk1 upon hormonal stimulation. In all vertebrates, release from prophase arrest relies on protein kinase A (PKA) downregulation and on the dephosphorylation of a long-sought but still unidentified substra...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4014304/ https://ncbi.nlm.nih.gov/pubmed/24525567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4318 |
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