Mutant astrocytes differentiated from Rett syndrome patients-specific iPSCs have adverse effects on wild-type neurons

The disease mechanism of Rett syndrome (RTT) is not well understood. Studies in RTT mouse models have suggested a non-cell-autonomous role for astrocytes in RTT pathogenesis. However, it is not clear whether this is also true for human RTT astrocytes. To establish an in vitro human RTT model, we pre...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Williams, Emily Cunningham, Zhong, Xiaofen, Mohamed, Ahmed, Li, Ronghui, Liu, Yan, Dong, Qiping, Ananiev, Gene E., Mok, Jonathan Chern Choong, Lin, Benjamin Ray, Lu, Jianfeng, Chiao, Cassandra, Cherney, Rachel, Li, Hongda, Zhang, Su-Chun, Chang, Qiang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2014
विषय:
Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014193/
https://ncbi.nlm.nih.gov/pubmed/24419315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu008
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