Structural basis of sialidase in complex with geranylated flavonoids as potent natural inhibitors

Sialidase catalyzes the removal of a terminal sialic acid from glycoconjugates and plays a pivotal role in nutrition, cellular interactions and pathogenesis mediating various infectious diseases including cholera, influenza and sepsis. An array of antiviral sialidase agents have been developed and a...

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Hlavní autoři: Lee, Youngjin, Ryu, Young Bae, Youn, Hyung-Seop, Cho, Jung Keun, Kim, Young Min, Park, Ji-Young, Lee, Woo Song, Park, Ki Hun, Eom, Soo Hyun
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2014
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014123/
https://ncbi.nlm.nih.gov/pubmed/24816104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004714002971
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