Structural basis of sialidase in complex with geranylated flavonoids as potent natural inhibitors

Sialidase catalyzes the removal of a terminal sialic acid from glycoconjugates and plays a pivotal role in nutrition, cellular interactions and pathogenesis mediating various infectious diseases including cholera, influenza and sepsis. An array of antiviral sialidase agents have been developed and a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lee, Youngjin, Ryu, Young Bae, Youn, Hyung-Seop, Cho, Jung Keun, Kim, Young Min, Park, Ji-Young, Lee, Woo Song, Park, Ki Hun, Eom, Soo Hyun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: International Union of Crystallography 2014
Pynciau:
Research Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014123/
https://ncbi.nlm.nih.gov/pubmed/24816104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004714002971
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