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A slow-forming isopeptide bond in the structure of the major pilin SpaD from Corynebacterium diphtheriae has implications for pilus assembly

The Gram-positive organism Corynebacterium diphtheriae, the cause of diphtheria in humans, expresses pili on its surface which it uses for adhesion and colonization of its host. These pili are covalent protein polymers composed of three types of pilin subunit that are assembled by specific sortase e...

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Bibliografiske detaljer
Main Authors: Kang, Hae Joo, Paterson, Neil G., Kim, Chae Un, Middleditch, Martin, Chang, Chungyu, Ton-That, Hung, Baker, Edward N.
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014117/
https://ncbi.nlm.nih.gov/pubmed/24816089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004714001400
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