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Sgt1 acts via an LKB1/AMPK pathway to establish cortical polarity in larval neuroblasts

Drosophila neuroblasts are a model system for studying stem cell self-renewal and the establishment of cortical polarity. Larval neuroblasts generate a large apical self-renewing neuroblast, and a small basal cell that differentiates. We performed a genetic screen to identify regulators of neuroblas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Andersen, Ryan O., Turnbull, Doug W., Johnson, Eric A., Doe, Chris Q.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013783/
https://ncbi.nlm.nih.gov/pubmed/22248825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.12.047
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