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Transgene IL-6 Enhances DC-Stimulated CTL Responses by Counteracting CD4(+)25(+)Foxp3(+) Regulatory T Cell Suppression via IL-6-Induced Foxp3 Downregulation
Dendritic cells (DCs), the most potent antigen-presenting cells have been extensively applied in clinical trials for evaluation of antitumor immunity. However, the efficacy of DC-mediated cancer vaccines is still limited as they are unable to sufficiently break the immune tolerance. In this study, w...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Molecular Diversity Preservation International (MDPI)
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4013578/ https://ncbi.nlm.nih.gov/pubmed/24690994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15045508 |
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