Intratumoural expression of IL-6/STAT3, IL-17 and FOXP3 immune cells in the immunosuppressive tumour microenvironment of colorectal cancer Immune cells-positive for IL-6, STAT3, IL-17 and FOXP3 and colorectal cancer development

Immune cells in the tumour microenvironment (TME) interact with each other and with tumour cells to promote tumour development. IL-6/STAT3 pathway induces and maintains mainly pro-tumour TME. Macrophages and lymphocytes are positive for IL-6, STAT3 and IL-17, while FoxP3 cells are mainly regulatory...

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Detalhes bibliográficos
Main Authors: Maya Vladova Gulubova, Dimitur Chavdarov Chonov, Koni Vancho Ivanova, Mariyna Kostova Hristova, Maria Magdalena Krasimirova-Ignatova, Tatyana Ivanova Vlaykova
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2022-12-01
Colecção:Biotechnology & Biotechnological Equipment
Assuntos:
IL-6
IL-17
FoxP3
STAT3
colorectal cancer
Acesso em linha:https://www.tandfonline.com/doi/10.1080/13102818.2022.2072765
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