Stability and Release Kinetics of an Advanced Gliclazide-Cholic Acid Formulation: The Use of Artificial-Cell Microencapsulation in Slow Release Targeted Oral Delivery of Antidiabetics

INTRODUCTION: In previous studies carried out in our laboratory, a bile acid (BA) formulation exerted a hypoglycaemic effect in a rat model of type-1 diabetes (T1D). When the antidiabetic drug gliclazide (G) was added to the bile acid, it augmented the hypoglycaemic effect. In a recent study, we des...

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Détails bibliographiques
Auteurs principaux: Mooranian, Armin, Negrulj, Rebecca, Mathavan, Sangeetha, Martinez, Jorge, Sciarretta, Jessica, Chen-Tan, Nigel, Mukkur, TK, Mikov, Momir, Lalic-Popovic, Mladena, Stojančević, Maja, Golocorbin-Kon, Svetlana, Al-Salami, Hani
Format: Artigo
Langue:Inglês
Publié: Springer US 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013442/
https://ncbi.nlm.nih.gov/pubmed/24829616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12247-014-9182-5
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