Probiotic Pre-treatment Reduces Gliclazide Permeation (ex vivo) in Healthy Rats but Increases It in Diabetic Rats to the Level Seen in Untreated Healthy Rats

AIM: To investigate the influence of probiotic pre-treatment on the permeation of the antidiabetic drug gliclazide in healthy and diabetic rats. METHODS: Wistar rats (age 2–3 months, weight 350 ± 50 g) were randomly allocated into one of 4 groups (N = 16 each group): healthy control, healthy probiot...

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Detalhes bibliográficos
Main Authors: Al-Salami, Hani, Butt, Grant, Tucker, Ian, Skrbic, Ranko, Golocorbin-Kon, Svetlana, Mikov, Momir
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2008
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817444/
https://ncbi.nlm.nih.gov/pubmed/20157366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1753-5174.2008.00006.x
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