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Diabetes and hypertension increase the placental and transcellular permeation of the lipophilic drug diazepam in pregnant women
BACKGROUND: Previous studies carried out in our laboratories have demonstrated impaired drug permeation in diabetic animals. In this study the permeation of diazepam (after a single dose of 5 mg/day, administered intramuscularly) will be investigated in diabetic and hypertensive pregnant women. METH...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3854538/ https://ncbi.nlm.nih.gov/pubmed/24134697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2393-13-188 |
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