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Inconsistent blood brain barrier disruption by intraarterial mannitol in rabbits: implications for chemotherapy

The novel ability to quantify drug and tracer concentrations in vivo by optical means leads to the possibility of detecting and quantifying blood brain barrier (BBB) disruption in real-time by monitoring concentrations of chromophores such as Evan's Blue. In this study, experiments were conduct...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Joshi, Shailendra, Ergin, Aysegul, Wang, Mei, Reif, Roberto, Zhang, Jane, Bruce, Jeffrey N., Bigio, Irving J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013427/
https://ncbi.nlm.nih.gov/pubmed/21153681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-010-0466-4
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